16 Hamilton-Toronto Express, otherwise known as the Hamilton QEW Express Service, is a GO Transit bus route in Ontario, Canada.
The route serves as a direct service between downtown Toronto and downtown Hamilton, as opposed to the more local Lakeshore West line service.
This route operates primarily on Highway 403, the Queen Elizabeth Way, or the QEW, and the Gardiner Expressway.
The 16 Hamilton-Toronto Express route is a daily service operating between Hamilton GO Centre and Union Station Bus Terminal.
Starting February 24, 2014, onboard "real-time bus service information" was first introduced on select route 12 and 16 trips, with a full roll out by summer 2014.